High-dose azathioprine pulse therapy as a new treatment option in patients with active Wegener's granulomatosis and lupus nephritis refractory or intolerant to cyclophosphamide.

Benenson, E; Fries, J W U; Heilig, B; Pollok, M; Rubbert, A

Benenson, E; Fries, J W U; Heilig, B; Pollok, M; Rubbert, A.

Affiliation

Benenson E; Medical Department I, University of Cologne, Cologne, 50924, Germany. Efim.Benenson@Uni-koeln.de

Clin Rheumatol ; 24(3): 251-7, 2005 Jun.

Article in En | MEDLINE | ID: mdl-15940558

Subject(s)

Azathioprine/administration & dosage; Cyclophosphamide/adverse effects; Granulomatosis with Polyangiitis/drug therapy; Immunosuppressive Agents/administration & dosage; Lupus Nephritis/drug therapy; Adult; Antibodies, Antineutrophil Cytoplasmic/blood; Biopsy; Dose-Response Relationship, Drug; Feasibility Studies; Female; Follow-Up Studies; Granulomatosis with Polyangiitis/pathology; Humans; Immunosuppressive Agents/adverse effects; Injections, Intravenous; Lupus Nephritis/blood; Lupus Nephritis/pathology; Magnetic Resonance Imaging; Male; Middle Aged; Pulse Therapy, Drug; Remission Induction; Safety; Treatment Outcome

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Collection: 01-internacional Database: MEDLINE Main subject: Azathioprine / Lupus Nephritis / Granulomatosis with Polyangiitis / Cyclophosphamide / Immunosuppressive Agents Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Clin Rheumatol Year: 2005 Document type: Article Affiliation country: Germany

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