Effects of famotidine, mosapride and tandospirone for treatment of functional dyspepsia.
Aliment Pharmacol Ther
; 21 Suppl 2: 37-41, 2005 Jun.
Article
in En
| MEDLINE
| ID: mdl-15943845
ABSTRACT
BACKGROUND:
An effective therapeutic strategy for functional dyspepsia (FD) has not been well-established.AIM:
We investigated and compared the therapeutic effects of famotidine, mosapride and tandospirone for the control of dyspeptic symptoms.METHODS:
Fully examined FD patients of outpatient clinics at seven different medical centres were enrolled in the study. They were randomly assigned to three groups based on the type of drug administered famotidine, mosapride and tandospirone. The effects of treatment over 4 weeks were assessed by visual analogue scales.RESULTS:
All of the drugs showed beneficial effects, although famotidine was the most effective for symptom relief, which was significantly greater than tandospirone, while the effect of mosapride was similar to that of famotidine. No subtype of FD showed a better response to a particular type of drug.CONCLUSIONS:
For the treatment of FD, famotidine demonstrated the best therapeutic effect, followed by mosapride, while that of tandospirone was significantly lower.
Search on Google
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Piperazines
/
Pyrimidines
/
Benzamides
/
Gastrointestinal Agents
/
Famotidine
/
Morpholines
/
Dyspepsia
/
Anti-Ulcer Agents
Type of study:
Clinical_trials
Limits:
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Aliment Pharmacol Ther
Journal subject:
FARMACOLOGIA
/
GASTROENTEROLOGIA
/
TERAPIA POR MEDICAMENTOS
Year:
2005
Document type:
Article
Affiliation country:
Japan