A Rac homolog functions downstream of Ras1 to control hyphal differentiation and high-temperature growth in the pathogenic fungus Cryptococcus neoformans.

Vallim, Marcelo A; Nichols, Connie B; Fernandes, Larissa; Cramer, Kari L; Alspaugh, J Andrew

Vallim, Marcelo A; Nichols, Connie B; Fernandes, Larissa; Cramer, Kari L; Alspaugh, J Andrew.

Affiliation

Vallim MA; Department of Medicine, Duke University Medical Center (DUMC) 3355, Durham, NC 27710, USA.

Eukaryot Cell ; 4(6): 1066-78, 2005 Jun.

Article in En | MEDLINE | ID: mdl-15947199

Subject(s)

Cryptococcus neoformans/physiology; Fungal Proteins; Hot Temperature; Hyphae/growth & development; rac GTP-Binding Proteins/genetics; rac GTP-Binding Proteins/metabolism; ras Proteins/metabolism; Base Sequence; Cryptococcus neoformans/cytology; Cryptococcus neoformans/genetics; Cryptococcus neoformans/growth & development; Cryptococcus neoformans/pathogenicity; DNA, Fungal; Gene Expression Regulation, Fungal; Genes, Fungal; Genome, Fungal; Mutation; Protein Serine-Threonine Kinases/metabolism; Two-Hybrid System Techniques; p21-Activated Kinases; ras Proteins/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Fungal Proteins / Ras Proteins / Rac GTP-Binding Proteins / Cryptococcus neoformans / Hyphae / Hot Temperature Language: En Journal: Eukaryot Cell Journal subject: BIOLOGIA MOLECULAR Year: 2005 Document type: Article Affiliation country: United States Country of publication: United States

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