GATA-4 binds to an upstream element of the human alpha2(I) collagen gene (COL1A2) and inhibits transcription in fibroblasts.

Wang, Lu; Tanaka, Shizuko; Ramirez, Francesco

Wang, Lu; Tanaka, Shizuko; Ramirez, Francesco.

Affiliation

Wang L; Laboratory of Genetics and Organogenesis, Research Division of the Hospital for Special Surgery, Department Physiology and Biophysics at Weill Medical College of Cornell University, New York, NY 10021, USA.

Matrix Biol ; 24(5): 333-40, 2005 Aug.

Article in En | MEDLINE | ID: mdl-15982862

Subject(s)

Collagen/genetics; Fibroblasts/metabolism; GATA4 Transcription Factor/metabolism; Response Elements/genetics; Transcription, Genetic; Animals; Base Sequence; Binding Sites; Collagen Type I; Conserved Sequence/genetics; DNA Footprinting; Humans; Mice; Molecular Sequence Data; Nucleic Acid Conformation

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Collection: 01-internacional Database: MEDLINE Main subject: Transcription, Genetic / Collagen / Response Elements / GATA4 Transcription Factor / Fibroblasts Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Matrix Biol Journal subject: BIOLOGIA MOLECULAR / BIOQUIMICA Year: 2005 Document type: Article Affiliation country: United States

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