Bradykinin B1 antagonists: SAR studies in the 2,3-diaminopyridine series.

Kuduk, Scott D; Chang, Ronald K; Ng, Christina; Murphy, Kathy L; Ransom, Richard W; Tang, Cuyue; Prueksaritanont, Thomayant; Freidinger, Roger M; Pettibone, Douglas J; Bock, Mark G

Kuduk, Scott D; Chang, Ronald K; Ng, Christina; Murphy, Kathy L; Ransom, Richard W; Tang, Cuyue; Prueksaritanont, Thomayant; Freidinger, Roger M; Pettibone, Douglas J; Bock, Mark G.

Affiliation

Kuduk SD; Department of Medicinal Chemistry, Sumneytown Pike, PO Box 4, West Point, PA 19486, USA. scott_d_kuduk@merck.com

Bioorg Med Chem Lett ; 15(17): 3925-9, 2005 Sep 01.

Article in En | MEDLINE | ID: mdl-15993596

Subject(s)

Aminopyridines/chemical synthesis; Bradykinin B1 Receptor Antagonists; Aminopyridines/pharmacokinetics; Aminopyridines/pharmacology; Animals; Bradykinin/antagonists & inhibitors; Humans; Pharmacokinetics; Protein Binding; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Bradykinin B1 Receptor Antagonists / Aminopyridines Limits: Animals / Humans Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2005 Document type: Article Affiliation country: United States Country of publication: United kingdom

Search on Google

Add to My VHL

XML

PubMed Links