Human CTLA4 knock-in mice unravel the quantitative link between tumor immunity and autoimmunity induced by anti-CTLA-4 antibodies.

Lute, Kenneth D; May, Kenneth F; Lu, Ping; Zhang, Huiming; Kocak, Ergun; Mosinger, Bedrick; Wolford, Christopher; Phillips, Gary; Caligiuri, Michael A; Zheng, Pan; Liu, Yang

Lute, Kenneth D; May, Kenneth F; Lu, Ping; Zhang, Huiming; Kocak, Ergun; Mosinger, Bedrick; Wolford, Christopher; Phillips, Gary; Caligiuri, Michael A; Zheng, Pan; Liu, Yang.

Affiliation

Lute KD; Division of Cancer Immunology, Department of Pathology, Center for Biostatistics, Columbus, OH, USA.

Blood ; 106(9): 3127-33, 2005 Nov 01.

Article in En | MEDLINE | ID: mdl-16037385

Subject(s)

Antibodies/immunology; Antigens, Differentiation/immunology; Antigens, Differentiation/metabolism; Autoimmunity/immunology; Neoplasms/immunology; Animals; Antibodies/pharmacology; Antigens, CD; Antigens, Differentiation/genetics; Autoimmunity/drug effects; CTLA-4 Antigen; Cell Line; Complement C3/metabolism; Humans; Kidney/immunology; Kidney/metabolism; Mice; Mice, Transgenic; Neoplasms/genetics; Neoplasms/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antigens, Differentiation / Autoimmunity / Antibodies / Neoplasms Limits: Animals / Humans Language: En Journal: Blood Year: 2005 Document type: Article Affiliation country: United States Country of publication: United States

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