The beta-1 adrenergic antagonist, betaxolol, improves working memory performance in rats and monkeys.

Ramos, Brian P; Colgan, Lesley; Nou, Eric; Ovadia, Shira; Wilson, Steven R; Arnsten, Amy F T

Ramos, Brian P; Colgan, Lesley; Nou, Eric; Ovadia, Shira; Wilson, Steven R; Arnsten, Amy F T.

Affiliation

Ramos BP; Department of Neurobiology, Yale University School of Medicine, New Haven, Connecticut 06520-8001, USA.

Biol Psychiatry ; 58(11): 894-900, 2005 Dec 01.

Article in En | MEDLINE | ID: mdl-16043136

Subject(s)

Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-Antagonists/pharmacology; Betaxolol/pharmacology; Memory, Short-Term/drug effects; Psychomotor Performance/drug effects; Adrenergic beta-Antagonists/toxicity; Animals; Attention/drug effects; Betaxolol/toxicity; Cognition/drug effects; Dose-Response Relationship, Drug; Hypnotics and Sedatives; Macaca mulatta; Male; Maze Learning/drug effects; Microinjections; Pancreatic Diseases/chemically induced; Prefrontal Cortex; Rats; Stereotaxic Techniques

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Collection: 01-internacional Database: MEDLINE Main subject: Psychomotor Performance / Betaxolol / Adrenergic beta-Antagonists / Adrenergic beta-1 Receptor Antagonists / Memory, Short-Term Limits: Animals Language: En Journal: Biol Psychiatry Year: 2005 Document type: Article Affiliation country: United States

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