Complete genome sequence and lytic phase transcription profile of a Coccolithovirus.
Science
; 309(5737): 1090-2, 2005 Aug 12.
Article
in En
| MEDLINE
| ID: mdl-16099989
ABSTRACT
The genus Coccolithovirus is a recently discovered group of viruses that infect the globally important marine calcifying microalga Emiliania huxleyi. Among the 472 predicted genes of the 407,339-base pair genome are a variety of unexpected genes, most notably those involved in biosynthesis of ceramide, a sphingolipid known to induce apoptosis. Uniquely for algal viruses, it also contains six RNA polymerase subunits and a novel promoter, suggesting this virus encodes its own transcription machinery. Microarray transcriptomic analysis reveals that 65% of the predicted virus-encoded genes are expressed during lytic infection of E. huxleyi.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Transcription, Genetic
/
Genome, Viral
/
Sequence Analysis, DNA
/
Phycodnaviridae
Language:
En
Journal:
Science
Year:
2005
Document type:
Article
Affiliation country:
United kingdom