Gleason grading and volume estimation in prostate needle biopsy specimens: evolving issues.
Am J Clin Pathol
; 123 Suppl: S58-66, 2005 Jun.
Article
in En
| MEDLINE
| ID: mdl-16100868
ABSTRACT
The Gleason grading system for prostate cancer is a powerful tool that can help choose therapy and predict outcome for patients. The clinical use and problem areas of the Gleason grading system are reviewed. The issues discussed include grade discrepancies between prostate biopsy and resection specimens, grading small foci of tumor, diagnosing and grading cribriform lesions, reporting the grade when 3 grades of cancer are present in a specimen, and assignment of grade when multiple cores of differing grades are present. Finally, differing ways of communicating tumor volume and the percentage of high-grade carcinoma in prostate biopsy cores are considered.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Prostatic Neoplasms
/
Biopsy, Needle
Type of study:
Prognostic_studies
Limits:
Humans
/
Male
Language:
En
Journal:
Am J Clin Pathol
Year:
2005
Document type:
Article
Affiliation country:
United States
Publication country:
ENGLAND
/
ESCOCIA
/
GB
/
GREAT BRITAIN
/
INGLATERRA
/
REINO UNIDO
/
SCOTLAND
/
UK
/
UNITED KINGDOM