Autoimmune syndromes in major histocompatibility complex (MHC) congenic strains of nonobese diabetic (NOD) mice. The NOD MHC is dominant for insulitis and cyclophosphamide-induced diabetes.

Wicker, L S; Appel, M C; Dotta, F; Pressey, A; Miller, B J; DeLarato, N H; Fischer, P A; Boltz, R C; Peterson, L B

Wicker, L S; Appel, M C; Dotta, F; Pressey, A; Miller, B J; DeLarato, N H; Fischer, P A; Boltz, R C; Peterson, L B.

Affiliation

Wicker LS; Department of Autoimmune Diseases Research, Merck Research Laboratories, Rahway, New Jersey 07065.

J Exp Med ; 176(1): 67-77, 1992 Jul 01.

Article in En | MEDLINE | ID: mdl-1613467

Subject(s)

Autoimmune Diseases/genetics; Diabetes Mellitus, Type 1/genetics; Major Histocompatibility Complex; Mice, Inbred NOD/genetics; Pancreatitis/genetics; Animals; Autoantibodies/analysis; Cyclophosphamide/toxicity; Female; Male; Mice; Mice, Inbred C57BL; Pancreas/pathology; Pancreatitis/pathology; Submandibular Gland/pathology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pancreatitis / Autoimmune Diseases / Mice, Inbred NOD / Diabetes Mellitus, Type 1 / Major Histocompatibility Complex Limits: Animals Language: En Journal: J Exp Med Year: 1992 Document type: Article Country of publication: United States

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