Amifostine and dexrazoxane enhance the rapid loss of bone mass and further deterioration of vertebrae architecture in female rats.

Mwale, F; Ciobanu, I; Demers, C N; Antoniou, J; Héon, S; Servant, N; Chalifour, L E

Mwale, F; Ciobanu, I; Demers, C N; Antoniou, J; Héon, S; Servant, N; Chalifour, L E.

Affiliation

Mwale F; Lady Davis Institute for Medical Research, Sir Mortimer B. Davis Jewish General Hospital, 3755 Chemin de la Cote St. Catherine, Montréal, QC H3T 1E2, Canada. fmwale@ldi.jgh

Calcif Tissue Int ; 77(3): 175-9, 2005 Sep.

Article in En | MEDLINE | ID: mdl-16151678

Subject(s)

Amifostine/pharmacology; Bone Density/drug effects; Cardiovascular Agents/pharmacology; Lumbar Vertebrae/drug effects; Radiation-Protective Agents/pharmacology; Razoxane/pharmacology; Animals; Antibiotics, Antineoplastic/pharmacology; Bone Resorption/drug therapy; Doxorubicin/pharmacology; Drug Therapy, Combination; Female; Femur/drug effects; Femur/metabolism; Femur/pathology; Lumbar Vertebrae/metabolism; Lumbar Vertebrae/pathology; Rats; Tomography, X-Ray Computed/methods

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Collection: 01-internacional Database: MEDLINE Main subject: Radiation-Protective Agents / Razoxane / Cardiovascular Agents / Bone Density / Amifostine / Lumbar Vertebrae Limits: Animals Language: En Journal: Calcif Tissue Int Year: 2005 Document type: Article Affiliation country: Canada Country of publication: United States

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