A posteriori respiratory gating in contrast ultrasound for assessment of hepatic perfusion.
Phys Med Biol
; 50(19): 4465-80, 2005 Oct 07.
Article
in En
| MEDLINE
| ID: mdl-16177483
ABSTRACT
An original strategy is proposed to minimize the impact of respiratory motion on hepatic contrast-enhanced ultrasound studies. It is based on the a posteriori triggering of dynamic image sequences. It was tested on perfusion studies acquired with a high temporal resolution (8 images s-1) to enable parametric imaging. A respiratory component was first estimated by independent component analysis. The estimation of the local minima and maxima of this curve enabled us to select two subsets of frames, corresponding to the end-of-inspiration plane and to the end-of-expiration plane. Both subsets were simultaneously analysed using factor analysis of medical image sequences. This method identified the main contrast uptake kinetics and their associated localizations. The global strategy was validated firstly on a simulated study and then applied to 11 patients' studies. In both cases, the frame selection was judged relevant and a necessary preliminary step before applying methods of parametric imaging. In conclusion, the a posteriori gating method that is proposed is a first step towards local quantification of hepatic contrast-enhanced ultrasound studies.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Respiration
/
Computer Simulation
/
Image Interpretation, Computer-Assisted
/
Contrast Media
/
Liver
/
Motion
Type of study:
Diagnostic_studies
/
Prognostic_studies
Limits:
Humans
Language:
En
Journal:
Phys Med Biol
Year:
2005
Document type:
Article
Affiliation country:
France