I. Poloxamer-formulated plasmid DNA-based human cytomegalovirus vaccine: evaluation of plasmid DNA biodistribution/persistence and integration.

Vilalta, Adrián; Mahajan, Rohit K; Hartikka, Jukka; Rusalov, Denis; Martin, Terrie; Bozoukova, Vesselina; Leamy, Vicky; Hall, Keith; Lalor, Peggy; Rolland, Alain; Kaslow, David C

Vilalta, Adrián; Mahajan, Rohit K; Hartikka, Jukka; Rusalov, Denis; Martin, Terrie; Bozoukova, Vesselina; Leamy, Vicky; Hall, Keith; Lalor, Peggy; Rolland, Alain; Kaslow, David C.

Affiliation

Vilalta A; Vical Incorporated, San Diego, CA 92121, USA. avilalta@vical.com

Hum Gene Ther ; 16(10): 1143-50, 2005 Oct.

Article in En | MEDLINE | ID: mdl-16218775

Subject(s)

Cytomegalovirus Vaccines/pharmacokinetics; Cytomegalovirus; Poloxamer/pharmacokinetics; Vaccines, DNA/pharmacokinetics; Viral Proteins/immunology; Animals; Cytomegalovirus/genetics; Cytomegalovirus/immunology; Cytomegalovirus Infections/genetics; Cytomegalovirus Infections/immunology; Cytomegalovirus Infections/prevention & control; Cytomegalovirus Vaccines/administration & dosage; Cytomegalovirus Vaccines/genetics; Cytomegalovirus Vaccines/immunology; Drug Evaluation, Preclinical; Humans; Injections, Intramuscular; Mice; Poloxamer/chemistry; Rabbits; Vaccines, DNA/administration & dosage; Vaccines, DNA/genetics; Vaccines, DNA/immunology; Viral Proteins/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Viral Proteins / Vaccines, DNA / Poloxamer / Cytomegalovirus Vaccines / Cytomegalovirus Limits: Animals / Humans Language: En Journal: Hum Gene Ther Journal subject: GENETICA MEDICA / TERAPEUTICA Year: 2005 Document type: Article Affiliation country: United States

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