Mutation in IRO1 tightly linked with URA3 gene reduces virulence of Candida albicans.
Microbiol Immunol
; 49(10): 937-9, 2005.
Article
in En
| MEDLINE
| ID: mdl-16237272
ABSTRACT
Gene deletion in the pathogenic fungus Candida albicans has relied heavily on a URA3 cassette and a recipient delta ura3 strain CAI4. The IRO1 gene adjacent to URA3 was inadvertently deleted during construction of CAI4. We report here that a mutation in IRO1 reduces virulence of C. albicans.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Transcription Factors
/
Virulence
/
Candida albicans
/
Fungal Proteins
Type of study:
Prognostic_studies
Limits:
Animals
Language:
En
Journal:
Microbiol Immunol
Year:
2005
Document type:
Article
Affiliation country:
Japan
Country of publication:
AU
/
AUSTRALIA
/
AUSTRÁLIA