Cardiac mitochondrial compromise in 1-yr-old Erythrocebus patas monkeys perinatally-exposed to nucleoside reverse transcriptase inhibitors.

Divi, Rao L; Leonard, Sarah L; Kuo, Maryanne M; Walker, Brettania L; Orozco, Christine C; St Claire, Marisa C; Nagashima, Kunio; Harbaugh, Steven W; Harbaugh, Jeffrey W; Thamire, Chandrasekhar; Sable, Craig A; Poirier, Miriam C

Divi, Rao L; Leonard, Sarah L; Kuo, Maryanne M; Walker, Brettania L; Orozco, Christine C; St Claire, Marisa C; Nagashima, Kunio; Harbaugh, Steven W; Harbaugh, Jeffrey W; Thamire, Chandrasekhar; Sable, Craig A; Poirier, Miriam C.

Affiliation

Divi RL; Center for Cancer Research, National Cancer Institute, NIH, 37 Convent Drive, Bethesda, MD 20892-4255, USA.

Cardiovasc Toxicol ; 5(3): 333-46, 2005.

Article in En | MEDLINE | ID: mdl-16244378

Subject(s)

Mitochondria, Heart/metabolism; Reverse Transcriptase Inhibitors/pharmacology; Animals; Animals, Newborn; Creatine Kinase/blood; DNA/biosynthesis; DNA/genetics; DNA, Mitochondrial/metabolism; Echocardiography; Electrocardiography; Erythrocebus; Female; Image Processing, Computer-Assisted; Lactic Acid/metabolism; Leukocyte Count; Luminescent Measurements; Microscopy, Electron, Transmission; Mitochondria, Heart/drug effects; Pregnancy; Ventricular Function, Left/drug effects; Ventricular Function, Left/physiology

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Collection: 01-internacional Database: MEDLINE Main subject: Reverse Transcriptase Inhibitors / Mitochondria, Heart Type of study: Guideline Limits: Animals / Pregnancy Language: En Journal: Cardiovasc Toxicol Journal subject: ANGIOLOGIA / CARDIOLOGIA / TOXICOLOGIA Year: 2005 Document type: Article Affiliation country: United States

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