Development of a time-resolved fluorometric assay for the high throughput screening of melanin concentrating hormone receptor antagonists.

Lee, Sunghou; Kim, Gun-Do; Park, Woo-Kyu; Cho, Heeyeong; Yoo, Sung-Eun

Lee, Sunghou; Kim, Gun-Do; Park, Woo-Kyu; Cho, Heeyeong; Yoo, Sung-Eun.

Affiliation

Lee S; Department of Biotechnology and Informatics, College of Engineering, Sangmyung University, San 98-20, Anseo-Dong, Cheonan 330-720, Republic of Korea. lees@smu.ac.kr

J Pharmacol Toxicol Methods ; 53(3): 242-7, 2006.

Article in En | MEDLINE | ID: mdl-16249102

Subject(s)

Fluorometry/methods; Melanins/antagonists & inhibitors; Piperidines/pharmacology; Pyrimidines/pharmacology; Receptors, Pituitary Hormone/antagonists & inhibitors; Receptors, Pituitary Hormone/analysis; Animals; Biological Assay; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Ligands; Melanins/genetics; Melanins/physiology; Mice; Radioligand Assay; Rats; Receptors, Pituitary Hormone/genetics; Receptors, Pituitary Hormone/metabolism; Reproducibility of Results; Sensitivity and Specificity; Time Factors

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Collection: 01-internacional Database: MEDLINE Main subject: Piperidines / Pyrimidines / Receptors, Pituitary Hormone / Fluorometry / Melanins Type of study: Diagnostic_studies / Screening_studies Limits: Animals / Humans Language: En Journal: J Pharmacol Toxicol Methods Journal subject: FARMACOLOGIA / TOXICOLOGIA Year: 2006 Document type: Article Country of publication: United States

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