Accelerated wound healing of alkali-burned corneas in MRL mice is associated with a reduced inflammatory signature.

Ueno, Motonobu; Lyons, Bonnie L; Burzenski, Lisa M; Gott, Bruce; Shaffer, Daniel J; Roopenian, Derry C; Shultz, Leonard D

Ueno, Motonobu; Lyons, Bonnie L; Burzenski, Lisa M; Gott, Bruce; Shaffer, Daniel J; Roopenian, Derry C; Shultz, Leonard D.

Affiliation

Ueno M; Jackson Laboratory, Bar Harbor, ME 04609, USA.

Invest Ophthalmol Vis Sci ; 46(11): 4097-106, 2005 Nov.

Article in En | MEDLINE | ID: mdl-16249486

Subject(s)

Burns, Chemical/metabolism; Corneal Diseases/metabolism; Eye Burns/chemically induced; Wound Healing/physiology; Animals; Bone Marrow Transplantation; Burns, Chemical/immunology; Burns, Chemical/pathology; Burns, Chemical/surgery; Carrier Proteins/genetics; Carrier Proteins/metabolism; Collagenases/genetics; Collagenases/metabolism; Corneal Diseases/immunology; Corneal Diseases/pathology; Corneal Diseases/surgery; Disease Models, Animal; Epithelium, Corneal/physiology; Flow Cytometry; Gene Expression Regulation/physiology; Male; Matrix Metalloproteinase 1; Matrix Metalloproteinases/genetics; Matrix Metalloproteinases/metabolism; Mice; Mice, Inbred C57BL; Mice, Inbred MRL lpr; Neutrophils/physiology; Oligonucleotide Array Sequence Analysis; RNA, Messenger/metabolism; Repressor Proteins/genetics; Repressor Proteins/metabolism; Reverse Transcriptase Polymerase Chain Reaction; Sodium Hydroxide; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling Proteins/genetics; Suppressor of Cytokine Signaling Proteins/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Wound Healing / Burns, Chemical / Eye Burns / Corneal Diseases Type of study: Prognostic_studies / Risk_factors_studies Language: En Journal: Invest Ophthalmol Vis Sci Year: 2005 Document type: Article Affiliation country: United States

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