Autoamplification of NFATc1 expression determines its essential role in bone homeostasis.

Asagiri, Masataka; Sato, Kojiro; Usami, Takako; Ochi, Sae; Nishina, Hiroshi; Yoshida, Hiroki; Morita, Ikuo; Wagner, Erwin F; Mak, Tak W; Serfling, Edgar; Takayanagi, Hiroshi

Asagiri, Masataka; Sato, Kojiro; Usami, Takako; Ochi, Sae; Nishina, Hiroshi; Yoshida, Hiroki; Morita, Ikuo; Wagner, Erwin F; Mak, Tak W; Serfling, Edgar; Takayanagi, Hiroshi.

Affiliation

Asagiri M; Department of Cell Signaling, Tokyo Medical and Dental University, Japan.

J Exp Med ; 202(9): 1261-9, 2005 Nov 07.

Article in En | MEDLINE | ID: mdl-16275763

Subject(s)

Bone and Bones/physiology; Homeostasis/genetics; NFATC Transcription Factors/genetics; NFATC Transcription Factors/physiology; Animals; Blastocyst/physiology; Cell Differentiation/genetics; Cells, Cultured; Epigenesis, Genetic/physiology; Fetal Tissue Transplantation/immunology; Liver/cytology; Mice; Mice, Knockout; NFATC Transcription Factors/biosynthesis; NFATC Transcription Factors/deficiency; Osteoclasts/cytology; Osteoclasts/physiology; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos/deficiency; Proto-Oncogene Proteins c-fos/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bone and Bones / NFATC Transcription Factors / Homeostasis Limits: Animals Language: En Journal: J Exp Med Year: 2005 Document type: Article Affiliation country: Japan

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