Red wine polyphenols influence carcinogenesis, intestinal microflora, oxidative damage and gene expression profiles of colonic mucosa in F344 rats.

Dolara, Piero; Luceri, Cristina; De Filippo, Carlotta; Femia, Angelo Pietro; Giovannelli, Lisa; Caderni, Giovanna; Cecchini, Cinzia; Silvi, Stefania; Orpianesi, Carla; Cresci, Alberto

Dolara, Piero; Luceri, Cristina; De Filippo, Carlotta; Femia, Angelo Pietro; Giovannelli, Lisa; Caderni, Giovanna; Cecchini, Cinzia; Silvi, Stefania; Orpianesi, Carla; Cresci, Alberto.

Affiliation

Dolara P; Department of Pharmacology, University of Florence, Viale G. Pieraccini 6, 50139 Florence, Italy. piero.dolara@unifi.it

Mutat Res ; 591(1-2): 237-46, 2005 Dec 11.

Article in En | MEDLINE | ID: mdl-16293270

Subject(s)

Colon/drug effects; Colon/physiology; Colonic Neoplasms/metabolism; Colonic Neoplasms/prevention & control; Flavonoids/pharmacology; Intestinal Mucosa; Phenols/pharmacology; Wine; 1,2-Dimethylhydrazine/toxicity; Animals; Anticarcinogenic Agents/administration & dosage; Anticarcinogenic Agents/pharmacology; Azoxymethane/toxicity; Carcinogens/toxicity; Colon/anatomy & histology; Colon/microbiology; Colonic Neoplasms/chemically induced; Colonic Neoplasms/pathology; Comet Assay; DNA Damage; Diet; Flavonoids/administration & dosage; Gene Expression Profiling; Gene Expression Regulation/drug effects; Humans; Intestinal Mucosa/drug effects; Intestinal Mucosa/microbiology; Intestinal Mucosa/physiology; Male; Oligonucleotide Array Sequence Analysis; Oxidation-Reduction; Phenols/administration & dosage; Polyphenols; Rats; Rats, Inbred F344

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Collection: 01-internacional Database: MEDLINE Main subject: Phenols / Wine / Flavonoids / Colon / Colonic Neoplasms / Intestinal Mucosa Limits: Animals / Humans / Male Language: En Journal: Mutat Res Year: 2005 Document type: Article Affiliation country: Italy Country of publication: Netherlands

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