Lactandrate: a D-homo-aza-androsterone alkylator in the treatment of breast cancer.

Trafalis, Dimitrios T P; Geromichalos, George D; Koukoulitsa, Catherine; Papageorgiou, Athanasios; Karamanakos, Panayiotis; Camoutsis, Charalambos

Trafalis, Dimitrios T P; Geromichalos, George D; Koukoulitsa, Catherine; Papageorgiou, Athanasios; Karamanakos, Panayiotis; Camoutsis, Charalambos.

Affiliation

Trafalis DT; Laboratory of Medicinal Chemistry, Faculty of Pharmacy, University of Patras, Patras, Greece. dtrafalis@yahoo.com

Breast Cancer Res Treat ; 97(1): 17-31, 2006 May.

Article in En | MEDLINE | ID: mdl-16319980

Subject(s)

Alkylating Agents/therapeutic use; Antineoplastic Agents/therapeutic use; Azasteroids/therapeutic use; Homosteroids/therapeutic use; Mammary Neoplasms, Experimental/drug therapy; Secosteroids/therapeutic use; Adenocarcinoma/drug therapy; Androsterone/therapeutic use; Animals; Cell Proliferation/drug effects; Estrogen Receptor alpha/metabolism; Female; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Molecular Structure; Tumor Cells, Cultured/drug effects

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Collection: 01-internacional Database: MEDLINE Main subject: Secosteroids / Azasteroids / Alkylating Agents / Homosteroids / Mammary Neoplasms, Experimental / Antineoplastic Agents Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Breast Cancer Res Treat Year: 2006 Document type: Article Affiliation country: Greece Country of publication: Netherlands

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