Multiple repair pathways mediate tolerance to chemotherapeutic cross-linking agents in vertebrate cells.

Nojima, Kuniharu; Hochegger, Helfrid; Saberi, Alihossein; Fukushima, Toru; Kikuchi, Koji; Yoshimura, Michio; Orelli, Brian J; Bishop, Douglas K; Hirano, Seiki; Ohzeki, Mioko; Ishiai, Masamichi; Yamamoto, Kazuhiko; Takata, Minoru; Arakawa, Hiroshi; Buerstedde, Jean-Marie; Yamazoe, Mitsuyoshi; Kawamoto, Takuo; Araki, Kasumi; Takahashi, Jun A; Hashimoto, Nobuo; Takeda, Shunichi; Sonoda, Eiichiro

Nojima, Kuniharu; Hochegger, Helfrid; Saberi, Alihossein; Fukushima, Toru; Kikuchi, Koji; Yoshimura, Michio; Orelli, Brian J; Bishop, Douglas K; Hirano, Seiki; Ohzeki, Mioko; Ishiai, Masamichi; Yamamoto, Kazuhiko; Takata, Minoru; Arakawa, Hiroshi; Buerstedde, Jean-Marie; Yamazoe, Mitsuyoshi; Kawamoto, Takuo; Araki, Kasumi; Takahashi, Jun A; Hashimoto, Nobuo; Takeda, Shunichi; Sonoda, Eiichiro.

Affiliation

Nojima K; Department of Radiation Genetics, Kyoto University, Japan.

Cancer Res ; 65(24): 11704-11, 2005 Dec 15.

Article in En | MEDLINE | ID: mdl-16357182

Subject(s)

Antineoplastic Agents, Alkylating/pharmacology; Cross-Linking Reagents/pharmacology; DNA Damage; DNA Repair; DNA/drug effects; Signal Transduction; Animals; Antigens, Nuclear/metabolism; Chickens; Cisplatin/pharmacology; DNA Replication/drug effects; DNA-Binding Proteins/metabolism; DNA-Directed DNA Polymerase/genetics; DNA-Directed DNA Polymerase/physiology; Epistasis, Genetic; Fanconi Anemia Complementation Group C Protein/genetics; Fanconi Anemia Complementation Group C Protein/physiology; Genes, rev/genetics; Genes, rev/physiology; Ku Autoantigen; Melphalan/pharmacology; Mitomycin/pharmacology; Nucleic Acid Synthesis Inhibitors/pharmacology; Recombination, Genetic/drug effects

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Collection: 01-internacional Database: MEDLINE Main subject: DNA Damage / DNA / Signal Transduction / Antineoplastic Agents, Alkylating / Cross-Linking Reagents / DNA Repair Limits: Animals Language: En Journal: Cancer Res Year: 2005 Document type: Article Affiliation country: Japan

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