Insulin-like growth factor binding protein-2 stimulates proliferation and activates multiple cascades of the mitogen-activated protein kinase pathways in NIH-OVCAR3 human epithelial ovarian cancer cells.

Chakrabarty, Shilla; Kondratick, Laura

Chakrabarty, Shilla; Kondratick, Laura.

Affiliation

Chakrabarty S; Department of Obstetrics & Gynecology, University of Texas Medical Branch, Galveston, Texas 77555-1066, USA. schakrab@utmb.edu

Cancer Biol Ther ; 5(2): 189-97, 2006 Feb.

Article in En | MEDLINE | ID: mdl-16357519

Subject(s)

Adenocarcinoma/enzymology; Insulin-Like Growth Factor Binding Protein 2/antagonists & inhibitors; Insulin-Like Growth Factor Binding Protein 2/pharmacology; MAP Kinase Signaling System/drug effects; Ovarian Neoplasms/enzymology; Antibodies/immunology; Antibodies/pharmacology; Cell Line, Tumor; Cell Proliferation/drug effects; Cytokines/metabolism; Enzyme Activation/drug effects; Female; Humans; Insulin-Like Growth Factor Binding Protein 2/immunology; Phosphorylation/drug effects

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Collection: 01-internacional Database: MEDLINE Main subject: Ovarian Neoplasms / Adenocarcinoma / Insulin-Like Growth Factor Binding Protein 2 / MAP Kinase Signaling System Limits: Female / Humans Language: En Journal: Cancer Biol Ther Journal subject: NEOPLASIAS / TERAPEUTICA Year: 2006 Document type: Article Affiliation country: United States Country of publication: United States

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