Caspase inhibition in apoptotic T cells triggers necrotic cell death depending on the cell type and the proapoptotic stimulus.

Scheller, Carsten; Knöferle, Johanna; Ullrich, Anett; Prottengeier, Johannes; Racek, Tomas; Sopper, Sieghart; Jassoy, Christian; Rethwilm, Axel; Koutsilieri, Eleni

Scheller, Carsten; Knöferle, Johanna; Ullrich, Anett; Prottengeier, Johannes; Racek, Tomas; Sopper, Sieghart; Jassoy, Christian; Rethwilm, Axel; Koutsilieri, Eleni.

Affiliation

Scheller C; Institute of Virology and Immunobiology, University of Würzburg, Versbacher Strasse 7, 97078 Würzburg, Germany. scheller@vim.uni-wuerzburg.de

J Cell Biochem ; 97(6): 1350-61, 2006 Apr 15.

Article in En | MEDLINE | ID: mdl-16365881

Subject(s)

Apoptosis/drug effects; Caspase Inhibitors; Necrosis/metabolism; T-Lymphocytes/metabolism; Amino Acid Chloromethyl Ketones/metabolism; Amino Acid Chloromethyl Ketones/pharmacology; Caspases/metabolism; Cell Death; Cell Line; Cysteine Proteinase Inhibitors/metabolism; Cysteine Proteinase Inhibitors/pharmacology; Humans; Signal Transduction; Time Factors; fas Receptor/metabolism; fas Receptor/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / Apoptosis / Caspase Inhibitors / Necrosis Limits: Humans Language: En Journal: J Cell Biochem Year: 2006 Document type: Article Affiliation country: Germany

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