Local activation of the nitric oxide/cyclic guanosine monophosphate pathway in growth cones regulates filopodial length via protein kinase G, cyclic ADP ribose and intracellular Ca2+ release.

Welshhans, Kristy; Rehder, Vincent

Welshhans, Kristy; Rehder, Vincent.

Affiliation

Welshhans K; Department of Biology, Georgia State University, PO Box 4010, Atlanta, GA 30302-4010, USA.

Eur J Neurosci ; 22(12): 3006-16, 2005 Dec.

Article in En | MEDLINE | ID: mdl-16367767

Subject(s)

Calcium/metabolism; Cyclic ADP-Ribose/metabolism; Growth Cones/enzymology; Guanosine Monophosphate/metabolism; Nitric Oxide/metabolism; Protein Kinase C/metabolism; Pseudopodia/physiology; Animals; Cells, Cultured; Diagnostic Imaging/methods; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors/pharmacology; Extracellular Space/drug effects; Extracellular Space/metabolism; Ganglia, Invertebrate/cytology; Growth Cones/drug effects; Helix, Snails; Hydrazines/pharmacology; Models, Biological; Neurons/classification; Neurons/cytology; Neurons/drug effects; Nitric Oxide/pharmacology; Nitric Oxide Donors/pharmacology; Pseudopodia/drug effects; Signal Transduction/physiology; Time Factors

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Collection: 01-internacional Database: MEDLINE Main subject: Pseudopodia / Protein Kinase C / Calcium / Guanosine Monophosphate / Growth Cones / Cyclic ADP-Ribose / Nitric Oxide Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals Language: En Journal: Eur J Neurosci Journal subject: NEUROLOGIA Year: 2005 Document type: Article Affiliation country: United States Country of publication: France

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