Lysophosphatidylserine stimulates L2071 mouse fibroblast chemotactic migration via a process involving pertussis toxin-sensitive trimeric G-proteins.

Park, Kyoung Sun; Lee, Ha-Young; Kim, Mi-Kyoung; Shin, Eun Ha; Jo, Seong Ho; Kim, Sang Doo; Im, Dong-Soon; Bae, Yoe-Sik

Park, Kyoung Sun; Lee, Ha-Young; Kim, Mi-Kyoung; Shin, Eun Ha; Jo, Seong Ho; Kim, Sang Doo; Im, Dong-Soon; Bae, Yoe-Sik.

Affiliation

Park KS; Medical Research Center for Cancer Molecular Therapy and Department of Biochemistry, College of Medicine, Dong-A University, Busan 602-714, Korea.

Mol Pharmacol ; 69(3): 1066-73, 2006 Mar.

Article in En | MEDLINE | ID: mdl-16368894

Subject(s)

Calcium/metabolism; Chemotaxis; Fibroblasts/drug effects; GTP-Binding Protein alpha Subunits, Gi-Go/physiology; Lysophospholipids/pharmacology; Animals; Calcium-Calmodulin-Dependent Protein Kinases/antagonists & inhibitors; Enzyme Activation; Estrenes/pharmacology; Extracellular Signal-Regulated MAP Kinases/metabolism; Fibroblasts/metabolism; Fibroblasts/physiology; Flavonoids/pharmacology; GTP-Binding Protein alpha Subunits, Gi-Go/antagonists & inhibitors; Mice; Pertussis Toxin/pharmacology; Phosphodiesterase Inhibitors/pharmacology; Phosphorylation; Proto-Oncogene Proteins c-akt/metabolism; Pyrrolidinones/pharmacology; Receptors, Lysophosphatidic Acid/antagonists & inhibitors; Sphingosine/analogs & derivatives; Sphingosine/pharmacology; p38 Mitogen-Activated Protein Kinases/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Lysophospholipids / Chemotaxis / Calcium / GTP-Binding Protein alpha Subunits, Gi-Go / Fibroblasts Type of study: Diagnostic_studies Limits: Animals Language: En Journal: Mol Pharmacol Year: 2006 Document type: Article Country of publication: United States

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