Anti-cancer effects of bortezomib against chemoresistant neuroblastoma cell lines in vitro and in vivo.

Michaelis, Martin; Fichtner, Iduna; Behrens, Diana; Haider, Wolfram; Rothweiler, Florian; Mack, Andreas; Cinatl, Jaroslav; Doerr, Hans Wilhelm; Cinatl, Jindrich

Michaelis, Martin; Fichtner, Iduna; Behrens, Diana; Haider, Wolfram; Rothweiler, Florian; Mack, Andreas; Cinatl, Jaroslav; Doerr, Hans Wilhelm; Cinatl, Jindrich.

Affiliation

Michaelis M; Institut für Medizinische Virologie, Klinikum der Johann Wolfgang Goethe-Universität, D-60596 Frankfurt am Main, Germany.

Int J Oncol ; 28(2): 439-46, 2006 Feb.

Article in En | MEDLINE | ID: mdl-16391799

Subject(s)

Antineoplastic Agents/pharmacology; Boronic Acids/pharmacology; Neuroblastoma/prevention & control; Pyrazines/pharmacology; Animals; Antibiotics, Antineoplastic/pharmacology; Antineoplastic Agents, Phytogenic/pharmacology; Apoptosis; Boronic Acids/administration & dosage; Bortezomib; Cell Cycle/drug effects; Cell Line, Tumor; Cell Survival/drug effects; Dose-Response Relationship, Drug; Doxorubicin/pharmacology; Drug Resistance, Neoplasm; Female; Humans; Mice; Mice, Nude; Neovascularization, Pathologic/prevention & control; Neuroblastoma/blood supply; Neuroblastoma/pathology; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines/administration & dosage; Vincristine/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Pyrazines / Boronic Acids / Neuroblastoma / Antineoplastic Agents Type of study: Clinical_trials Limits: Animals / Female / Humans Language: En Journal: Int J Oncol Journal subject: NEOPLASIAS Year: 2006 Document type: Article Affiliation country: Germany Country of publication: Greece

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