IL-10 deficiency leads to somatic mutations in a model of IBD.

Sato, Yuichirou; Takahashi, Seiichi; Kinouchi, Yoshitaka; Shiraki, Manabu; Endo, Katsuya; Matsumura, Yoshifumi; Kakuta, Yoichi; Tosa, Masaki; Motida, Atsuhiro; Abe, Hiroko; Imai, Go; Yokoyama, Hiroshi; Nomura, Eiki; Negoro, Kenichi; Takagi, Sho; Aihara, Hiroyuki; Masumura, Ken-ichi; Nohmi, Takehiko; Shimosegawa, Tooru

Sato, Yuichirou; Takahashi, Seiichi; Kinouchi, Yoshitaka; Shiraki, Manabu; Endo, Katsuya; Matsumura, Yoshifumi; Kakuta, Yoichi; Tosa, Masaki; Motida, Atsuhiro; Abe, Hiroko; Imai, Go; Yokoyama, Hiroshi; Nomura, Eiki; Negoro, Kenichi; Takagi, Sho; Aihara, Hiroyuki; Masumura, Ken-ichi; Nohmi, Takehiko; Shimosegawa, Tooru.

Affiliation

Sato Y; Department of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Japan. ysatou@int3.med.tohoku.ac.jp

Carcinogenesis ; 27(5): 1068-73, 2006 May.

Article in En | MEDLINE | ID: mdl-16407368

Subject(s)

Inflammatory Bowel Diseases/genetics; Interleukin-10/genetics; Interleukin-10/physiology; Mutation; Animals; Colonic Neoplasms/genetics; DNA Mutational Analysis; Disease Models, Animal; Female; Gene Deletion; Gene Frequency; Genes, Reporter; Inflammation; Male; Mice; Mice, Inbred C57BL

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Collection: 01-internacional Database: MEDLINE Main subject: Inflammatory Bowel Diseases / Interleukin-10 / Mutation Type of study: Prognostic_studies Limits: Animals Language: En Journal: Carcinogenesis Year: 2006 Document type: Article Affiliation country: Japan Country of publication: United kingdom

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