Role of cannabinoid receptors in Delta-9-tetrahydrocannabinol suppression of IL-12p40 in mouse bone marrow-derived dendritic cells infected with Legionella pneumophila.

Lu, Tangying; Newton, Cathy; Perkins, Izabella; Friedman, Herman; Klein, Thomas W

Lu, Tangying; Newton, Cathy; Perkins, Izabella; Friedman, Herman; Klein, Thomas W.

Affiliation

Lu T; Department of Medical Microbiology and Immunology, MDC 10 University of South Florida College of Medicine, 12901 Bruce B. Downs Blvd., Tampa, FL 33612, USA.

Eur J Pharmacol ; 532(1-2): 170-7, 2006 Feb 17.

Article in En | MEDLINE | ID: mdl-16443217

Subject(s)

Dendritic Cells/drug effects; Dronabinol/pharmacology; Interleukin-12/metabolism; Legionella pneumophila/growth & development; Receptors, Cannabinoid/physiology; Animals; Bone Marrow Cells/drug effects; Bone Marrow Cells/metabolism; Bone Marrow Cells/microbiology; Capsaicin/analogs & derivatives; Capsaicin/pharmacology; Cells, Cultured; Dendritic Cells/metabolism; Dendritic Cells/microbiology; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Gene Expression/drug effects; Hallucinogens/pharmacology; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Pertussis Toxin/pharmacology; Protein Subunits/metabolism; RNA, Messenger/genetics; RNA, Messenger/metabolism; Receptor, Cannabinoid, CB1/genetics; Receptor, Cannabinoid, CB1/physiology; Receptor, Cannabinoid, CB2/genetics; Receptor, Cannabinoid, CB2/physiology; Receptors, Cannabinoid/genetics; TRPV Cation Channels/antagonists & inhibitors; TRPV Cation Channels/physiology

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Collection: 01-internacional Database: MEDLINE Main subject: Dronabinol / Dendritic Cells / Legionella pneumophila / Interleukin-12 / Receptors, Cannabinoid Limits: Animals Language: En Journal: Eur J Pharmacol Year: 2006 Document type: Article Affiliation country: United States Country of publication: Netherlands

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