Computational approaches to model ligand selectivity in drug design.

Ortiz, Angel R; Gomez-Puertas, Paulino; Leo-Macias, Alejandra; Lopez-Romero, Pedro; Lopez-Viñas, Eduardo; Morreale, Antonio; Murcia, Marta; Wang, Kun

Ortiz, Angel R; Gomez-Puertas, Paulino; Leo-Macias, Alejandra; Lopez-Romero, Pedro; Lopez-Viñas, Eduardo; Morreale, Antonio; Murcia, Marta; Wang, Kun.

Affiliation

Ortiz AR; Bioinformatics Unit, Centro de Biologia Molecular Severo Ochoa (CSIC-UAM) Cantoblanco, 28049 Madrid, Spain. aro@cbm.uam.es

Curr Top Med Chem ; 6(1): 41-55, 2006.

Article in En | MEDLINE | ID: mdl-16454757

Subject(s)

Computer-Aided Design; Drug Design; Models, Molecular; Amino Acid Sequence; Chemistry, Pharmaceutical; Choline O-Acetyltransferase/chemistry; Choline O-Acetyltransferase/metabolism; Enzyme Inhibitors/chemistry; Enzyme Inhibitors/pharmacology; Humans; Ligands; Molecular Sequence Data; Protein Kinases/chemistry; Protein Kinases/metabolism; Quantitative Structure-Activity Relationship; Serine Endopeptidases/chemistry; Serine Endopeptidases/metabolism; Substrate Specificity

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Collection: 01-internacional Database: MEDLINE Main subject: Drug Design / Models, Molecular / Computer-Aided Design Limits: Humans Language: En Journal: Curr Top Med Chem Journal subject: QUIMICA Year: 2006 Document type: Article Affiliation country: Spain Country of publication: United Arab Emirates

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