Apoptosis, necrosis and cell proliferation-inhibition by cyclosporine A in U937 cells (a human monocytic cell line).

Roy, Molay Kumar; Takenaka, Makiko; Kobori, Masuko; Nakahara, Kazuhiko; Isobe, Seiichiro; Tsushida, Tojiro

Roy, Molay Kumar; Takenaka, Makiko; Kobori, Masuko; Nakahara, Kazuhiko; Isobe, Seiichiro; Tsushida, Tojiro.

Affiliation

Roy MK; National Food Research Institute, 2-1-9, Kannondai, Tsukuba, Ibaraki 305-0051, Japan. mkroy@affrc.go.jp

Pharmacol Res ; 53(3): 293-302, 2006 Mar.

Article in En | MEDLINE | ID: mdl-16458014

Subject(s)

Apoptosis/drug effects; Cell Proliferation/drug effects; Cyclosporine/toxicity; Immunosuppressive Agents/toxicity; Mitochondria/drug effects; Aspartic Acid/analogs & derivatives; Aspartic Acid/pharmacology; Caspase 3; Caspase Inhibitors; Caspases/metabolism; Cell Survival/drug effects; Cytochromes c/metabolism; Dose-Response Relationship, Drug; Humans; Membrane Potentials; Mitochondria/enzymology; Necrosis; Protease Inhibitors/pharmacology; Time Factors; U937 Cells

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Collection: 01-internacional Database: MEDLINE Main subject: Cyclosporine / Apoptosis / Cell Proliferation / Immunosuppressive Agents / Mitochondria Limits: Humans Language: En Journal: Pharmacol Res Journal subject: FARMACOLOGIA Year: 2006 Document type: Article Affiliation country: Japan Country of publication: Netherlands

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