Design and synthesis of 7H-pyrrolo[2,3-d]pyrimidines as focal adhesion kinase inhibitors. Part 2.

Choi, Ha-Soon; Wang, Zhicheng; Richmond, Wendy; He, Xiaohui; Yang, Kunyong; Jiang, Tao; Karanewsky, Donald; Gu, Xiang-ju; Zhou, Vicki; Liu, Yi; Che, Jianwei; Lee, Christian C; Caldwell, Jeremy; Kanazawa, Takanori; Umemura, Ichiro; Matsuura, Naoko; Ohmori, Osamu; Honda, Toshiyuki; Gray, Nathanael; He, Yun

Choi, Ha-Soon; Wang, Zhicheng; Richmond, Wendy; He, Xiaohui; Yang, Kunyong; Jiang, Tao; Karanewsky, Donald; Gu, Xiang-ju; Zhou, Vicki; Liu, Yi; Che, Jianwei; Lee, Christian C; Caldwell, Jeremy; Kanazawa, Takanori; Umemura, Ichiro; Matsuura, Naoko; Ohmori, Osamu; Honda, Toshiyuki; Gray, Nathanael; He, Yun.

Affiliation

Choi HS; Genomics Institute of the Novartis Research Foundation (GNF), 10715 John Jay Hopkins Drive, San Diego, CA 920121, USA.

Bioorg Med Chem Lett ; 16(10): 2689-92, 2006 May 15.

Article in En | MEDLINE | ID: mdl-16524731

Subject(s)

Enzyme Inhibitors/chemistry; Enzyme Inhibitors/chemical synthesis; Focal Adhesion Protein-Tyrosine Kinases/antagonists & inhibitors; Pyrimidines/chemistry; Pyrimidines/chemical synthesis; Enzyme Inhibitors/pharmacology; Molecular Structure; Pyrimidines/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Pyrimidines / Enzyme Inhibitors / Focal Adhesion Protein-Tyrosine Kinases Language: En Journal: Bioorg Med Chem Lett Journal subject: BIOQUIMICA / QUIMICA Year: 2006 Document type: Article Affiliation country: United States

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