Cyclin dependent kinase inhibitors prevent apoptosis of postmitotic mouse motoneurons.

Appert-Collin, A; Hugel, B; Levy, R; Niederhoffer, N; Coupin, G; Lombard, Y; André, P; Poindron, P; Gies, J P

Appert-Collin, A; Hugel, B; Levy, R; Niederhoffer, N; Coupin, G; Lombard, Y; André, P; Poindron, P; Gies, J P.

Affiliation

Appert-Collin A; Université Louis Pasteur, Faculté de Pharmacie, UMR7175-LC1, BP 24, F-67401 Illkirch Cedex, France.

Life Sci ; 79(5): 484-90, 2006 Jun 27.

Article in En | MEDLINE | ID: mdl-16530228

Subject(s)

Apoptosis/drug effects; Cyclin-Dependent Kinases/antagonists & inhibitors; Mitosis; Motor Neurons/cytology; Motor Neurons/drug effects; Protein Kinase Inhibitors/pharmacology; Animals; Cell Survival/drug effects; Cells, Cultured; Cyclin D1/metabolism; Cyclin E/metabolism; Cyclin-Dependent Kinases/metabolism; Flavonoids/pharmacology; Kinetin/pharmacology; Mice; Nerve Growth Factors/deficiency; Piperidines/pharmacology; Purines/pharmacology; Roscovitine

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Collection: 01-internacional Database: MEDLINE Main subject: Apoptosis / Cyclin-Dependent Kinases / Protein Kinase Inhibitors / Mitosis / Motor Neurons Limits: Animals Language: En Journal: Life Sci Year: 2006 Document type: Article Affiliation country: France Country of publication: Netherlands

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