Temporal changes in concentrations of serum amyloid-A and haptoglobin and their associations with weight gain in neonatal reindeer calves.
Comp Immunol Microbiol Infect Dis
; 29(2-3): 79-88, 2006.
Article
in En
| MEDLINE
| ID: mdl-16551478
ABSTRACT
Age-related changes in serum concentrations of two acute phase proteins (APPs), haptoglobin (Hp) and serum amyloid-A (SAA) were investigated in newborn reindeer calves. Repeated blood samples were obtained from 51 reindeer calves at ages 0-32 days (2-4 samples from each calf). An increase of SAA concentrations was observed during the first 2 weeks of life. However, by the end of the observation period, SAA concentrations had decreased to levels below those of the first week. Serum Hp concentrations increased throughout the observation period. SAA concentrations in the second week had a negative association with weight gain during the entire study period (4 months). These time-related changes in APP concentrations suggest that these proteins have a role in the defence and adaptation mechanisms of newborn reindeer calves. Possible reasons for these changes include the presence of APP mediators in the colostrum, exposure to environmental pathogens after birth and age-related changes in hepatic synthesis of APP.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Serum Amyloid A Protein
/
Haptoglobins
/
Reindeer
/
Weight Gain
Type of study:
Risk_factors_studies
Limits:
Animals
Language:
En
Journal:
Comp Immunol Microbiol Infect Dis
Year:
2006
Document type:
Article
Affiliation country:
Finland