Asiaticoside induces human collagen I synthesis through TGFbeta receptor I kinase (TbetaRI kinase)-independent Smad signaling.

Lee, Jongsung; Jung, Eunsun; Kim, Youngji; Park, Junho; Park, Jinil; Hong, Sungtaek; Kim, Jieun; Hyun, Changgu; Kim, Yeong Shik; Park, Deokhoon

Lee, Jongsung; Jung, Eunsun; Kim, Youngji; Park, Junho; Park, Jinil; Hong, Sungtaek; Kim, Jieun; Hyun, Changgu; Kim, Yeong Shik; Park, Deokhoon.

Affiliation

Lee J; Biospectrum Life Science Institute, Gunpo City, Gyunggi Do, Korea.

Planta Med ; 72(4): 324-8, 2006 Mar.

Article in En | MEDLINE | ID: mdl-16557473

Subject(s)

Centella; Collagen Type I/drug effects; Keratolytic Agents/pharmacology; Phytotherapy; Plant Extracts/pharmacology; Triterpenes/pharmacology; Blotting, Western; Collagen Type I/biosynthesis; Fibroblasts/drug effects; Fibroblasts/metabolism; Humans; Keratolytic Agents/administration & dosage; Keratolytic Agents/therapeutic use; Plant Extracts/administration & dosage; Plant Extracts/therapeutic use; Protein Serine-Threonine Kinases/metabolism; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Signal Transduction; Skin Aging; Smad3 Protein/metabolism; Smad4 Protein/metabolism; Triterpenes/administration & dosage; Triterpenes/therapeutic use

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Collection: 01-internacional Database: MEDLINE Main subject: Triterpenes / Plant Extracts / Centella / Collagen Type I / Keratolytic Agents / Phytotherapy Limits: Humans Language: En Journal: Planta Med Year: 2006 Document type: Article Country of publication: Germany

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