An epidemic of hepatitis A attributable to the ingestion of raw clams in Shanghai, China.
J Infect Dis
; 164(5): 852-9, 1991 Nov.
Article
in En
| MEDLINE
| ID: mdl-1658157
ABSTRACT
An epidemic of hepatitis A in 1988 in Shanghai had an overall attack rate of 4083/100,000 population (292,301 cases). The epidemic curve showed three peaks in January and February. A case-control study of 1208 matched pairs supported that clams were the vehicle for the virus (summary odds ratio, 9.47; P less than .001). Analysis of subsets who had eaten clams indicated that only 3.5% with hepatitis A had cooked their clams compared with 18.1% without hepatitis A, and those with the disease consumed more clams. A historical cohort study indicated that approximately 31.7% of the population had eaten clams one or more times between 9 December 1987 and 3 January 1988. The estimated attack rates in those who had and had not eaten clams were 11.93% and 0.52%, respectively (relative risk, 22.94; attributable risk, 11.41%). The three peaks in the consumption curve correlated with those in the epidemic curve. Hepatitis A virus was demonstrated in clams taken from the Shanghai markets and from the catching area.
Search on Google
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Disease Outbreaks
/
Bivalvia
/
Hepatovirus
/
Food Microbiology
/
Hepatitis A
Type of study:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Risk_factors_studies
Limits:
Adolescent
/
Adult
/
Animals
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
/
Middle aged
Country/Region as subject:
Asia
Language:
En
Journal:
J Infect Dis
Year:
1991
Document type:
Article
Affiliation country:
Canada