Loss of the VHR dual-specific phosphatase causes cell-cycle arrest and senescence.

Rahmouni, Souad; Cerignoli, Fabio; Alonso, Andres; Tsutji, Toshiya; Henkens, Rachel; Zhu, Changjun; Louis-dit-Sully, Christine; Moutschen, Michel; Jiang, Wei; Mustelin, Tomas

Rahmouni, Souad; Cerignoli, Fabio; Alonso, Andres; Tsutji, Toshiya; Henkens, Rachel; Zhu, Changjun; Louis-dit-Sully, Christine; Moutschen, Michel; Jiang, Wei; Mustelin, Tomas.

Affiliation

Rahmouni S; The Burnham Institute for Medical Research, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA.

Nat Cell Biol ; 8(5): 524-31, 2006 May.

Article in En | MEDLINE | ID: mdl-16604064

Subject(s)

Cell Division/physiology; Cellular Senescence/physiology; Protein Tyrosine Phosphatases/deficiency; Protein Tyrosine Phosphatases/metabolism; S Phase/physiology; Animals; COS Cells; Cells, Cultured; Chlorocebus aethiops; DNA/biosynthesis; Dual Specificity Phosphatase 3; Extracellular Signal-Regulated MAP Kinases/metabolism; HeLa Cells; Humans; JNK Mitogen-Activated Protein Kinases/metabolism; MAP Kinase Kinase Kinases/metabolism; Protein Tyrosine Phosphatases/genetics; RNA, Small Interfering/genetics

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Cell Division / S Phase / Protein Tyrosine Phosphatases / Cellular Senescence Type of study: Etiology_studies Limits: Animals / Humans Language: En Journal: Nat Cell Biol Year: 2006 Document type: Article Affiliation country: United States Country of publication: United kingdom

Search on Google

Add to My VHL

XML

PubMed Links