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Substituted 1,4-benzodiazepine-2,5-diones as alpha-helix mimetic antagonists of the HDM2-p53 protein-protein interaction.
Cummings, Maxwell D; Schubert, Carsten; Parks, Daniel J; Calvo, Raul R; LaFrance, Louis V; Lattanze, Jennifer; Milkiewicz, Karen L; Lu, Tianbao.
Affiliation
  • Cummings MD; Johnson & Johnson Pharmaceutical Research & Development, Exton, PA 19341, USA. mcumming@prdus.jnj.com
Chem Biol Drug Des ; 67(3): 201-5, 2006 Mar.
Article in En | MEDLINE | ID: mdl-16611213
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Collection: 01-internacional Database: MEDLINE Main subject: Benzodiazepines / Drug Design / Tumor Suppressor Protein p53 / Molecular Mimicry / Protein Interaction Mapping / Proto-Oncogene Proteins c-mdm2 Type of study: Prognostic_studies Limits: Humans Language: En Journal: Chem Biol Drug Des Journal subject: BIOQUIMICA / FARMACIA / FARMACOLOGIA Year: 2006 Document type: Article Affiliation country: United States Country of publication: United kingdom
Search on Google
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Collection: 01-internacional Database: MEDLINE Main subject: Benzodiazepines / Drug Design / Tumor Suppressor Protein p53 / Molecular Mimicry / Protein Interaction Mapping / Proto-Oncogene Proteins c-mdm2 Type of study: Prognostic_studies Limits: Humans Language: En Journal: Chem Biol Drug Des Journal subject: BIOQUIMICA / FARMACIA / FARMACOLOGIA Year: 2006 Document type: Article Affiliation country: United States Country of publication: United kingdom