T-cell epitopes of the La/SSB autoantigen: prediction based on the homology modeling of HLA-DQ2/DQ7 with the insulin-B peptide/HLA-DQ8 complex.

Kosmopoulou, Aggeliki; Vlassi, Metaxia; Stavrakoudis, Athanassios; Sakarellos, Constantinos; Sakarellos-Daitsiotis, Maria

Kosmopoulou, Aggeliki; Vlassi, Metaxia; Stavrakoudis, Athanassios; Sakarellos, Constantinos; Sakarellos-Daitsiotis, Maria.

Affiliation

Kosmopoulou A; Laboratory of Peptide Chemistry, Department of Chemistry, University of Ioannina, Ioannina 44110, Greece.

J Comput Chem ; 27(9): 1033-44, 2006 Jul 15.

Article in En | MEDLINE | ID: mdl-16639700

Subject(s)

Autoantigens/chemistry; Epitopes, T-Lymphocyte/chemistry; Epitopes, T-Lymphocyte/immunology; HLA-DQ Antigens/chemistry; Insulin/chemistry; Insulin/immunology; Models, Molecular; Ribonucleoproteins/chemistry; Amino Acid Sequence; Autoantigens/immunology; Computer Simulation; Crystallography, X-Ray; HLA-DQ Antigens/immunology; Humans; Molecular Sequence Data; Peptide Fragments/chemistry; Peptide Fragments/immunology; Protein Binding; Protein Structure, Quaternary; Protein Structure, Tertiary; Ribonucleoproteins/immunology; Sequence Alignment; Software; Structural Homology, Protein; SS-B Antigen

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Collection: 01-internacional Database: MEDLINE Main subject: Ribonucleoproteins / Autoantigens / Models, Molecular / HLA-DQ Antigens / Epitopes, T-Lymphocyte / Insulin Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: J Comput Chem Journal subject: QUIMICA Year: 2006 Document type: Article Affiliation country: Greece Country of publication: United States

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