Sterol regulatory element-binding protein 1 mediates liver X receptor-beta-induced increases in insulin secretion and insulin messenger ribonucleic acid levels.

Zitzer, Heike; Wente, Wolf; Brenner, Martin B; Sewing, Sabine; Buschard, Karsten; Gromada, Jesper; Efanov, Alexander M

Zitzer, Heike; Wente, Wolf; Brenner, Martin B; Sewing, Sabine; Buschard, Karsten; Gromada, Jesper; Efanov, Alexander M.

Affiliation

Zitzer H; Lilly Research Laboratories, Essener Bogen 7, D-22419 Hamburg, Germany.

Endocrinology ; 147(8): 3898-905, 2006 Aug.

Article in En | MEDLINE | ID: mdl-16644917

Subject(s)

DNA-Binding Proteins/metabolism; Insulin/genetics; Insulin/metabolism; Receptors, Cytoplasmic and Nuclear/metabolism; Sterol Regulatory Element Binding Protein 1/metabolism; Alternative Splicing; Animals; Cell Line, Tumor; DNA-Binding Proteins/agonists; Gene Expression Regulation/physiology; Glucose Intolerance/metabolism; Glucose Intolerance/physiopathology; Homeodomain Proteins/genetics; Homeodomain Proteins/metabolism; Hydrocarbons, Fluorinated; Insulin Secretion; Insulinoma; Islets of Langerhans/cytology; Liver X Receptors; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Orphan Nuclear Receptors; Pancreatic Neoplasms; RNA, Messenger/metabolism; RNA, Small Interfering; Receptors, Cytoplasmic and Nuclear/agonists; Sterol Regulatory Element Binding Protein 1/genetics; Sulfonamides/pharmacology; Trans-Activators/genetics; Trans-Activators/metabolism

Search on Google

Add to My VHL

XML

PubMed Links

Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Cytoplasmic and Nuclear / DNA-Binding Proteins / Sterol Regulatory Element Binding Protein 1 / Insulin Limits: Animals Language: En Journal: Endocrinology Year: 2006 Document type: Article Affiliation country: Germany Country of publication: United States

Search on Google

Add to My VHL

XML

PubMed Links