A selective peroxisome proliferator-activated receptor gamma modulator with distinct fat cell regulation properties.

Fujimura, Takao; Kimura, Chiaki; Oe, Tomoya; Takata, Yoko; Sakuma, Hiroyuki; Aramori, Ichiro; Mutoh, Seitaro

Fujimura, Takao; Kimura, Chiaki; Oe, Tomoya; Takata, Yoko; Sakuma, Hiroyuki; Aramori, Ichiro; Mutoh, Seitaro.

Affiliation

Fujimura T; Molecular Medicine Research Laboratories, Astellas Pharma Inc., Tsukuba, Ibaraki, Japan. takao.fujimura@jp.astellas.com

J Pharmacol Exp Ther ; 318(2): 863-71, 2006 Aug.

Article in En | MEDLINE | ID: mdl-16682454

Subject(s)

Adipocytes/drug effects; Benzimidazoles/pharmacology; PPAR gamma/drug effects; 3',5'-Cyclic-AMP Phosphodiesterases/biosynthesis; 3',5'-Cyclic-AMP Phosphodiesterases/genetics; 3T3 Cells; Animals; Cell Differentiation/drug effects; Chlorocebus aethiops; Collagen; Cyclic Nucleotide Phosphodiesterases, Type 3; Gels; Gene Expression/drug effects; Hypoglycemic Agents/pharmacology; Insulin Resistance; Mice; Obesity/physiopathology; PPAR gamma/genetics; Pioglitazone; Plasmids; RNA, Messenger/biosynthesis; RNA, Messenger/genetics; Reverse Transcriptase Polymerase Chain Reaction; Rosiglitazone; Thiazolidinediones/pharmacology; Triglycerides/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Benzimidazoles / Adipocytes / PPAR gamma Limits: Animals Language: En Journal: J Pharmacol Exp Ther Year: 2006 Document type: Article Affiliation country: Japan Country of publication: United States

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