New symmetrical quinazoline derivatives selectively induce apoptosis in human cancer cells.

Cubedo, Elena; Cordeu, Lucia; Bandres, Eva; Rebollo, Amaia; Malumbres, Raquel; Sanmartin, Carmen; Font, Maria; Palop, Juan Antonio; Gacía-Foncillas, Jesús

Cubedo, Elena; Cordeu, Lucia; Bandres, Eva; Rebollo, Amaia; Malumbres, Raquel; Sanmartin, Carmen; Font, Maria; Palop, Juan Antonio; Gacía-Foncillas, Jesús.

Affiliation

Cubedo E; Laboratorio de Farmacogenómica, Area de Oncología, Centro de Investigación Médica Aplicada, Pamplona, Spain. ecubgil@alumni.unav.es

Cancer Biol Ther ; 5(7): 850-9, 2006 Jul.

Article in En | MEDLINE | ID: mdl-16760648

Subject(s)

Antineoplastic Agents/therapeutic use; Neoplasms/drug therapy; Quinazolines/therapeutic use; Antineoplastic Agents/chemistry; Antineoplastic Agents/pharmacology; Apoptosis; Caspase 3/metabolism; Caspase Inhibitors; Cell Cycle/drug effects; Cell Line, Tumor; Cysteine Proteinase Inhibitors/pharmacology; Drug Evaluation, Preclinical; Genes, Neoplasm/drug effects; Humans; Neoplasms/enzymology; Neoplasms/genetics; Oligonucleotide Array Sequence Analysis; Quinazolines/chemistry; Quinazolines/pharmacology; RNA, Neoplasm/analysis

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Collection: 01-internacional Database: MEDLINE Main subject: Quinazolines / Neoplasms / Antineoplastic Agents Limits: Humans Language: En Journal: Cancer Biol Ther Journal subject: NEOPLASIAS / TERAPEUTICA Year: 2006 Document type: Article Affiliation country: Spain Country of publication: United States

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