Mouse spinal cord compression injury is reduced by either activation of the adenosine A2A receptor on bone marrow-derived cells or deletion of the A2A receptor on non-bone marrow-derived cells.

Li, Y; Oskouian, R J; Day, Y-J; Rieger, J M; Liu, L; Kern, J A; Linden, J

Li, Y; Oskouian, R J; Day, Y-J; Rieger, J M; Liu, L; Kern, J A; Linden, J.

Affiliation

Li Y; Department of Medicine, University of Virginia Health System, MR5 Box 801394, Charlottesville, VA 22908, USA.

Neuroscience ; 141(4): 2029-39, 2006 Sep 15.

Article in En | MEDLINE | ID: mdl-16777350

Subject(s)

Bone Marrow Cells/metabolism; Bone Marrow Transplantation/methods; Receptor, Adenosine A2A/genetics; Receptor, Adenosine A2A/metabolism; Spinal Cord Compression/metabolism; Spinal Cord Compression/therapy; Adenosine A2 Receptor Agonists; Analysis of Variance; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Activation/drug effects; Female; Mice; Mice, Knockout; Motor Activity/drug effects; Motor Activity/physiology; Myelin Sheath/pathology; Piperidines/chemistry; Piperidines/pharmacology; Radioligand Assay/methods; Spinal Cord Compression/pathology; Spinal Cord Compression/physiopathology; Time Factors; Triazines/pharmacokinetics; Triazoles/pharmacokinetics

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Collection: 01-internacional Database: MEDLINE Main subject: Spinal Cord Compression / Bone Marrow Cells / Bone Marrow Transplantation / Receptor, Adenosine A2A Type of study: Prognostic_studies Limits: Animals Language: En Journal: Neuroscience Year: 2006 Document type: Article Affiliation country: United States Country of publication: United States

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