Involvement of nuclear factor-kappaB in the inhibition of pro-inflammatory mediators by pinosylvin.

Lee, Jongsung; Jung, Eunsun; Lim, Jihee; Lee, Jiyoung; Hur, Sungran; Kim, Sang Suk; Lim, Sangbin; Hyun, Chang-Gu; Kim, Yeong Shik; Park, Deokhoon

Lee, Jongsung; Jung, Eunsun; Lim, Jihee; Lee, Jiyoung; Hur, Sungran; Kim, Sang Suk; Lim, Sangbin; Hyun, Chang-Gu; Kim, Yeong Shik; Park, Deokhoon.

Affiliation

Lee J; Biospectrum Life Science Institute, Gunpo City, Gyunggi Do, Republic of Korea.

Planta Med ; 72(9): 801-6, 2006 Jul.

Article in En | MEDLINE | ID: mdl-16783695

Subject(s)

Anti-Inflammatory Agents/pharmacology; Cytokines/metabolism; NF-kappa B/physiology; Stilbenes/pharmacology; Binding Sites; Cell Line; Cyclooxygenase 2/genetics; Cyclooxygenase 2 Inhibitors/pharmacology; Gene Expression Regulation/drug effects; Genes, Reporter; Humans; I-kappa B Proteins/metabolism; Interleukin-8/antagonists & inhibitors; Interleukin-8/genetics; Lipopolysaccharides/antagonists & inhibitors; Luciferases/analysis; NF-kappa B/antagonists & inhibitors; NF-kappa B/metabolism; Phosphorylation; Pinus/chemistry; Promoter Regions, Genetic; Signal Transduction/drug effects; Stilbenes/chemistry; Tumor Necrosis Factor-alpha/antagonists & inhibitors; Tumor Necrosis Factor-alpha/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Stilbenes / Cytokines / NF-kappa B / Anti-Inflammatory Agents Limits: Humans Language: En Journal: Planta Med Year: 2006 Document type: Article Country of publication: Germany

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