Structure-function relationships in the neuropeptide S receptor: molecular consequences of the asthma-associated mutation N107I.

Bernier, Virginie; Stocco, Rino; Bogusky, Michael J; Joyce, Joseph G; Parachoniak, Christine; Grenier, Karl; Arget, Michael; Mathieu, Marie-Claude; O'Neill, Gary P; Slipetz, Deborah; Crackower, Michael A; Tan, Christopher M; Therien, Alex G

Bernier, Virginie; Stocco, Rino; Bogusky, Michael J; Joyce, Joseph G; Parachoniak, Christine; Grenier, Karl; Arget, Michael; Mathieu, Marie-Claude; O'Neill, Gary P; Slipetz, Deborah; Crackower, Michael A; Tan, Christopher M; Therien, Alex G.

Affiliation

Bernier V; Department of Biochemistry and Molecular Biology, Merck Frosst Center for Therapeutic Research, Kirkland, Quebec H9H 3L1, Canada.

J Biol Chem ; 281(34): 24704-12, 2006 Aug 25.

Article in En | MEDLINE | ID: mdl-16790440

Subject(s)

Receptors, Neuropeptide/chemistry; Amino Acid Sequence; Asthma/genetics; Asthma/metabolism; Cell Line; Humans; Models, Molecular; Molecular Sequence Data; Mutation; Neuropeptides/chemistry; Neuropeptides/genetics; Neuropeptides/metabolism; Protein Binding; Protein Conformation; Receptors, G-Protein-Coupled/chemistry; Receptors, G-Protein-Coupled/genetics; Receptors, G-Protein-Coupled/metabolism; Receptors, Neuropeptide/genetics; Receptors, Neuropeptide/metabolism; Structure-Activity Relationship; Transfection

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Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Neuropeptide Type of study: Risk_factors_studies Limits: Humans Language: En Journal: J Biol Chem Year: 2006 Document type: Article Affiliation country: Canada

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