A lack of adriamycin (ADR) resistance in Chinese hamster ovary (CHO) cells overexpressing P-glycoprotein (Pgp) following in vitro exposure to fractionated X-irradiation.

Whelan, R D; Hosking, L K; Hill, B T

Whelan, R D; Hosking, L K; Hill, B T.

Affiliation

Whelan RD; Laboratory of Cellular Chemotherapy, Imperial Cancer Research Fund Laboratories, Lincoln's Inn Fields, London, U.K.

Biochem Soc Trans ; 19(2): 125S, 1991 Apr.

Article in En | MEDLINE | ID: mdl-1679723

Subject(s)

Cell Survival/radiation effects; Doxorubicin/pharmacology; Drug Resistance/genetics; Membrane Glycoproteins/genetics; ATP Binding Cassette Transporter, Subfamily B, Member 1; Animals; Biological Transport/drug effects; Cell Line; Cell Survival/drug effects; Cricetinae; Cricetulus; Doxorubicin/metabolism; Drug Resistance/radiation effects; Female; Gene Expression; Ovary; Verapamil/pharmacology; Vincristine/metabolism; Vincristine/pharmacology; X-Rays

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Collection: 01-internacional Database: MEDLINE Main subject: Drug Resistance / Membrane Glycoproteins / Doxorubicin / Cell Survival Limits: Animals Language: En Journal: Biochem Soc Trans Year: 1991 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom

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