A randomized phase III prospective trial of bethanechol to prevent radiotherapy-induced salivary gland damage in patients with head and neck cancer.

Jham, Bruno Correia; Teixeira, Inah Vanetti; Aboud, Clarissa Gonçalves; Carvalho, André Lopes; Coelho, Márcio de Matos; Freire, Addah Regina da Silva

Jham, Bruno Correia; Teixeira, Inah Vanetti; Aboud, Clarissa Gonçalves; Carvalho, André Lopes; Coelho, Márcio de Matos; Freire, Addah Regina da Silva.

Affiliation

Jham BC; Department of Oral Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Av Antônio Carlos, 6627, Pampulha, Belo Horizonte, 31270-901 Minas Gerais, Brazil. brunocjham@yahoo.com.br

Oral Oncol ; 43(2): 137-42, 2007 Feb.

Article in En | MEDLINE | ID: mdl-16798061

Subject(s)

Bethanechol/therapeutic use; Head and Neck Neoplasms/radiotherapy; Radiation Injuries/prevention & control; Salivary Glands/radiation effects; Xerostomia/prevention & control; Adult; Aged; Female; Head and Neck Neoplasms/pathology; Humans; Male; Middle Aged; Neoplasm Staging; Radiation Injuries/etiology; Radiotherapy/adverse effects; Saliva, Artificial/therapeutic use; Salivary Glands/injuries; Salivation/drug effects; Salivation/radiation effects; Treatment Outcome; Xerostomia/etiology

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Collection: 01-internacional Database: MEDLINE Main subject: Radiation Injuries / Salivary Glands / Xerostomia / Bethanechol / Head and Neck Neoplasms Type of study: Clinical_trials / Etiology_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Oral Oncol Journal subject: NEOPLASIAS Year: 2007 Document type: Article Affiliation country: Brazil

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