Alternative complement pathway activation is essential for inflammation and joint destruction in the passive transfer model of collagen-induced arthritis.

Banda, Nirmal K; Thurman, Joshua M; Kraus, Damian; Wood, Allyson; Carroll, Michael C; Arend, William P; Holers, V Michael

Banda, Nirmal K; Thurman, Joshua M; Kraus, Damian; Wood, Allyson; Carroll, Michael C; Arend, William P; Holers, V Michael.

Affiliation

Banda NK; Divisions of Rheumatology, University of Colorado Health Sciences Center, Denver, CO 80262, USA.

J Immunol ; 177(3): 1904-12, 2006 Aug 01.

Article in En | MEDLINE | ID: mdl-16849503

Subject(s)

Arthritis, Experimental/immunology; Arthritis, Experimental/pathology; Cartilage, Articular/immunology; Cartilage, Articular/pathology; Collagen/immunology; Complement Pathway, Alternative/immunology; Immunization, Passive; Animals; Antibodies, Monoclonal/administration & dosage; Arthritis, Experimental/genetics; Complement C3/chemistry; Complement C4/deficiency; Complement C4/genetics; Complement Factor B/deficiency; Complement Factor B/genetics; Complement Factor H/chemistry; Complement Inactivator Proteins/biosynthesis; Complement Inactivator Proteins/genetics; Cytokines/biosynthesis; Cytokines/genetics; Disease Models, Animal; Immunization, Passive/methods; Immunohistochemistry; Inflammation/genetics; Inflammation/immunology; Inflammation/pathology; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; RNA, Messenger/biosynthesis; Synovial Membrane/immunology; Synovial Membrane/metabolism; Synovial Membrane/pathology

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Collection: 01-internacional Database: MEDLINE Main subject: Arthritis, Experimental / Cartilage, Articular / Collagen / Immunization, Passive / Complement Pathway, Alternative Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Immunol Year: 2006 Document type: Article Affiliation country: United States

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