Induction of complete remission in a patient with acute myeloid leukemia refractory to high-dose chemotherapy through treatment with 5-azacytidine.
Leuk Res
; 31(3): 407-9, 2007 Mar.
Article
in En
| MEDLINE
| ID: mdl-16890286
ABSTRACT
For patients with acute myeloid leukemia refractory to intensive chemotherapy prognosis is very poor and treatment options are limited. 5-Azacytidine, a demethylating drug, is effective in the treatment of myelodysplastic syndromes when administered at a low-dose, subcutaneously. We report a case of a patient with AML refractory to induction chemotherapy as well as to two high-dose salvage regimens. The patient achieved CR through monotherapy with low-dose azacytidine.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Azacitidine
/
Antineoplastic Combined Chemotherapy Protocols
/
Leukemia, Myeloid
/
Drug Resistance, Neoplasm
Type of study:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Female
/
Humans
/
Middle aged
Language:
En
Journal:
Leuk Res
Year:
2007
Document type:
Article
Affiliation country:
Germany