Diazoxide preconditioning alleviates apoptosis of hippocampal neurons induced by anoxia-reoxygenation in vitro through up-regulation of Bcl-2/Bax protein ratio.

Liu, Rong-Guo; Wang, Wei-Jian; Song, Na; Chen, Yan-Qing; Li, Li-Huan

Liu, Rong-Guo; Wang, Wei-Jian; Song, Na; Chen, Yan-Qing; Li, Li-Huan.

Affiliation

Liu RG; Department of Anesthesiology, Fujian Provincial Hospital, Fuzhou, China.

Sheng Li Xue Bao ; 58(4): 345-50, 2006 Aug 25.

Article in En | MEDLINE | ID: mdl-16906335

Subject(s)

Apoptosis/drug effects; Diazoxide/pharmacology; Hippocampus/cytology; Ischemic Preconditioning/methods; Reperfusion Injury/prevention & control; Animals; Animals, Newborn; Cell Hypoxia; Neurons/cytology; Primary Cell Culture; Proto-Oncogene Proteins c-bcl-2/genetics; Proto-Oncogene Proteins c-bcl-2/metabolism; Rats; Rats, Sprague-Dawley; bcl-2-Associated X Protein/genetics; bcl-2-Associated X Protein/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Reperfusion Injury / Apoptosis / Ischemic Preconditioning / Diazoxide / Hippocampus Limits: Animals Language: En Journal: Sheng Li Xue Bao Year: 2006 Document type: Article Affiliation country: China Country of publication: China

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