BCR-ABL fusion regions as a source of multiple leukemia-specific CD8+ T-cell epitopes.

Kessler, J H; Bres-Vloemans, S A; van Veelen, P A; de Ru, A; Huijbers, I J G; Camps, M; Mulder, A; Offringa, R; Drijfhout, J W; Leeksma, O C; Ossendorp, F; Melief, C J M

Kessler, J H; Bres-Vloemans, S A; van Veelen, P A; de Ru, A; Huijbers, I J G; Camps, M; Mulder, A; Offringa, R; Drijfhout, J W; Leeksma, O C; Ossendorp, F; Melief, C J M.

Affiliation

Kessler JH; Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands. J.H.Kessler@lumc.nl

Leukemia ; 20(10): 1738-50, 2006 Oct.

Article in En | MEDLINE | ID: mdl-16932347

Subject(s)

CD8-Positive T-Lymphocytes/immunology; Cancer Vaccines/immunology; Epitopes, T-Lymphocyte/immunology; Fusion Proteins, bcr-abl/immunology; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/immunology; Amino Acid Sequence; Cell Line, Tumor; Epitope Mapping/methods; Fusion Proteins, bcr-abl/genetics; Fusion Proteins, bcr-abl/metabolism; HLA-A Antigens/immunology; HLA-A Antigens/metabolism; HLA-A2 Antigen; HLA-B Antigens/immunology; HLA-B Antigens/metabolism; HLA-B51 Antigen; HLA-C Antigens/immunology; HLA-C Antigens/metabolism; Humans; Immunotherapy/methods; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/therapy; Molecular Sequence Data; Peptide Fragments/genetics; Peptide Fragments/immunology; Peptide Fragments/metabolism; Protein Binding/immunology

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Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Fusion Proteins, bcr-abl / CD8-Positive T-Lymphocytes / Epitopes, T-Lymphocyte / Cancer Vaccines Type of study: Risk_factors_studies Limits: Humans Language: En Journal: Leukemia Journal subject: HEMATOLOGIA / NEOPLASIAS Year: 2006 Document type: Article Affiliation country: Netherlands Country of publication: United kingdom

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